Peripheral neuropathy caused by anticancer drugs
Conditions
Interventions
acupuncture
circular skin needle
no treatment
Sponsors
Shimane University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Within 3 years after completion of taxanes as preoperative or postoperative adjuvant chemotherapy for cancer. 2) Common Terminology Criteria for Adverse Events (CTCAE-JCOG v5.0) Grade 2 or higher symptoms of peripheral neuropathy (peripheral motor neuropathy, peripheral sensation) Neuropathy or neuralgia). 3) Outpatient visits are possible during the treatment and observation period. 4) After receiving sufficient explanations for participation in this research, with full understanding, document consent was obtained by the person's free will. 5) The age at the time of consent is between 20 and 80 years old.
Exclusion criteria
Exclusion criteria: 1) Peripheral neuropathy falls under any of the following. Neurologic symptoms that may be caused by sciatica or radiculopathy Neurologic symptoms thought to be caused by peripheral nerve strangulation such as tarsal tunnel syndrome Extremity sensory abnormalities that may be caused by cerebrovascular disorders Peripheral peripheral circulatory disturbance based on obstructive arteriosclerosis or Raynaud's disease Diabetic neuropathy Numbness worsens after bathing. 2) It is difficult to receive acupuncture due to metal allergy. 3) Major organ functions such as liver function, kidney function, pulmonary function, and hemostatic function are severely impaired 4) A woman who is or may be pregnant. 5) Concomitant with psychosis or symptom, it is difficult to understand clinical trials. 6) In addition, the doctor responsible for research (sharing) determined that it was inappropriate.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Degree of numbness in the foot due to Visual Analogue Scale (VAS) [After 12 weeks] | — |
Countries
Japan
Contacts
Public ContactRika TOUMA
Shimane University Hospital Clinical Research Center
Outcome results
None listed