patients who are scheduled to undergo highly invasive abdominal surgery
Conditions
Interventions
Oral intake of probiotics for 2 weeks.
Oral intake of prebiotics for 2 weeks.
Oral intake of synbiotics for 2 weeks.
Sponsors
Nagoya Unviersity
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients who are scheduled to undergo highly invasive abdominal surgery; including major hepatectomy, hepatopancreatoduodenectomy, pancreatoduodenectomy, pancreatectomy with celiac axis resection, subtotal esophagectomy, and other equivalent highly invasive abdominal surgery.
Exclusion criteria
Exclusion criteria: Patients who refused to participate the study. Patients with severe cognitive disorder. Patients who are not eligible for this study according to the physician's decision.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Compare the changes of intestinal microenvironment profile, fecal organic acid concentrations, and pH before and after an administration of probiotics, prebiotics, and synbiotics. | — |
Secondary
| Measure | Time frame |
|---|---|
| Compare the changes of blood tests before and after an administration of probiotics, prebiotics, and synbiotics. | — |
Countries
Japan
Contacts
Public ContactYukihiro Yokoyama
Nagoya University Department of Surgery, Division of Surgical Oncology
Outcome results
None listed