Comparison in clinical effect of conventional NSAIDs versus open-label placebos on patients with chronic pain.

Randomized noninferiority trial of conventional NSAIDs versus open-label placebos in patients with chronic pain. - Open-label placebo trial for chronic pain.

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000038070

Enrollment

Registered

2019-09-21

Start date

2019-07-11

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic Pain

Interventions

Conventional NSAIDs Open-label placebos

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Subjects who have had chronic pain for more than 3 months and voluntary participation in the study. 2. Subjects who take loxoprofen or celecoxib for more than 3 months 3. Pain intensity is more than one out of 10.

Exclusion criteria

Exclusion criteria: 1. Age<20, or >84 years old. 2. Disagree with participating in the study. 3. Under treatment of malignant tumors, vertebral fractures, and infections. 4. Within 3 months after any surgeries. 5. Under treatment of dementia 6. Suspect of cognitive impairment 7. Persons who investigators regard as inappropriate for participation.

Design outcomes

Primary

Measure	Time frame
Numerical rating scale	—

Secondary

Measure	Time frame
Pain Disability Assessment Scale EuroQol-5dimensions	—

Countries

Japan

Contacts

Public ContactTATSUNORI IKEMOTO

Aichi medical university Dept of Orthopaedics

tatsunon31-ik@umin.ac.jp+81561611809

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026