Feasibility study of risk reducing mastectomy (RRM) for BRCA1/2 mutation carriers

Feasibility study of risk reducing mastectomy (RRM) for BRCA1/2 mutation carriers - Feasibility study of risk reducing mastectomy (RRM) for BRCA1/2 mutation carriers

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000038061

Enrollment

Registered

2019-09-19

Start date

2019-10-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hereditary breast and ovarian cancer

Interventions

risk reducing mastectomy

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: 1.Woman with breast cancer in the past 2.BRCA1/2 mutation carriers who received genetic counseling 3.ECOG Performance Status=0, 1 4.Informed consent

Exclusion criteria

Exclusion criteria: 1.The case in which doctor does not approve to perform RRM 2.Pregnant woman or woman with a possibility of pregnant 3.Doctor's decision not to be registered to this study

Design outcomes

Primary

Measure	Time frame
Safety of RRM for BRCA1/2 mutation carriers Incidence of complications related to surgery	—

Secondary

Measure	Time frame
Incidence of occult breast cancer for RRM Incidence of breast cancer during 2 years after RRM	—

Countries

Japan

Contacts

Public ContactMao Kimoto

Mie University Hospital breast center

murata-c@clin.medic.mie-u.ac.jp0592321111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026