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The effect of compression therapy using surgical gloves on taxane-induced peripheral neuropathy(randomized control trial)

The effect of compression therapy using surgical gloves on taxane-induced peripheral neuropathy(randomized control trial) - compression therapy(taxane)

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000038056
Enrollment
300
Registered
2019-11-01
Start date
2019-11-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

lung cancer, gastric cancer, esophageal cancer, breast cancer, endometrial cancer, cervical cancer, ovarian cancer, pancreatic cancer

Interventions

Compression therapy with surgical Gloves all cycle from 30 minutes before administration of taxane therapy to 30 minutes after administration no preventation

Sponsors

Hitachi general hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: patients with lung cancer, gastric cancer, esophageal cancer, breast cancer, endometrial cancer, cervical cancer, ovarian cancer, and pancreatic cancer who receive taxane-containing-regimen porfomance status 0-2 patients who do not have latex allergy Taxane naive patients who got written informed consent

Exclusion criteria

Exclusion criteria: patients who have CTCAE more than grade1 neuropathy

Design outcomes

Primary

MeasureTime frame
The incidence of taxane-induced peripheral neuropathy grade 2 or higher using the CTCAE version 5.0.

Secondary

MeasureTime frame
The incidence of peripheral neuropathy grade B,C,D,E using Patient Neurotoxicity Questionnairethe (PNQ). The incidence of skin and nail tissue disorders using the CTCAE version 5.0. Time to skin and nail tissue disorders The incidence of taxane-induced peripheral neuropathy grade 1.3.4 using the CTCAE version 5.0. Time to peripheral neuropathy Ratio of cases dropping out

Countries

Japan

Contacts

Public ContactTakuya Suyama

Hitachi general hospital hematology,oncology

sutaku2468@yahoo.co.jp0294231111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026