A multicenter retrospective study on evaluation of the risk of lymph node metastasis using CRP genetic polymorphism in pT1cN0 thoracic esophageal squamous cell carcinoma

A multicenter retrospective study on evaluation of the risk of lymph node metastasis using CRP genetic polymorphism in pT1cN0 thoracic esophageal squamous cell carcinoma - Evaluation of the risk of lymph node metastasis using CRP genetic polymorphism in thoracic esophageal cancer

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000038043

Enrollment

645

Registered

2019-09-19

Start date

2019-10-17

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

pT1cN0 thoracic esophageal squamous cell carcinoma

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. pT1a-MM (ly+ and/or v+) or pT1b, cN0M0 primary thoracic squamous cell esophageal carcinoma. 2. Performed esophagectomy with 2 or 3-field lymph node adenectomy after 2007. 3. Examined lymph node metastasis pathologically. 3. Patients obtained informed consents. 4. Patients who can collect blood at the time of study.

Exclusion criteria

Exclusion criteria: 1. Received neoadjuvant therapy. 2. Had double cancers diagnosed 3 years before or 2 years after esophagectomy. 3. Within 2 years after esophagectomy. 4. Had prior surgery in mediastimun.

Design outcomes

Primary

Measure	Time frame
Negative predictive value to diagnose lymph node metastasis	—

Countries

Japan

Contacts

Public ContactSatoru Motoyama

Akita University Graduate School of Medicine

motoyama@doc.med.akita-u.ac018-834-1111

Outcome results