sterility
Conditions
Interventions
Anti-biotic agent
probiotic preparations
Sponsors
Sunkeikai Medical Corporation
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: (1) failure of implantation after at least two consecutive high-quality embryo transfers in fresh or frozen-thaw cycles, (2) possession of at least one high-quality embryo at the time of study inclusion, (3) no current smoking habit by either couple and (4) written consent for study participation.
Exclusion criteria
Exclusion criteria: (1) performing PGT-A, (2) diagnosed with antiphospholipid antibody syndrome, (3) using sperm retrieved by TESE for any reason, (4) morphological abnormalities in the myometrium or endometrium evident on transvaginal ultrasonography at the inclusion, and (5) having a chocolate cyst of 3 cm or more. (6) A history of antibiotics, steroids, immunosuppressive drugs, or vaginal suppositories within two weeks of endometrial tissue collection.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Bacterial flora during infertility treatment | — |
Secondary
| Measure | Time frame |
|---|---|
| Cumulative on-going rate and on-going transition (change over time) after bacterial flora testing and intervention | — |
Countries
Japan
Contacts
Public ContactShinnosuke Komiya
HORAC grand front Osaka Clinic medical office
Outcome results
None listed