Basic research on neoantigen analysis in patients with gastrointestinal solid cancer

Basic research on neoantigen analysis in patients with gastrointestinal solid cancer - Basic research on neoantigen analysis in patients with gastrointestinal solid cancer

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000038017

Enrollment

Registered

2019-10-01

Start date

2019-10-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

gastrointestinal solid cancer

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. The gastrointestinal tract is the primary, and pathologically diagnosed as adenocarcinoma or squamous cell carcinoma. 2. The registration date is over 20 years old. 3. Performance status (PS) is 0 to 1. 4. No history of chemotherapy, radiation therapy, endocrine therapy, or immunosuppressive therapy, including other carcinomas. 5. Organ function is maintained. 6. The patient has given written consent to participate in the study.

Exclusion criteria

Exclusion criteria: The patient has not given written consent.

Design outcomes

Primary

Measure	Time frame
Tumor-specific CTLs are induced by iPSDCs-ivtRNA derived from cancer-bearing patients to evaluate the immune response against neoantigen.	—

Countries

Japan

Contacts

Public ContactToshiyasu Ojima

Wakayama Medical University School of Medicine Second Department of Surgery

tojima@wakayama-med.ac.jp073-441-0613

Outcome results