Influence of ingestion of eicosapentaenoic acid-rich fish oil on muscle damage and delayed onset muscle soreness following eccentric contractions: a randomized, double-blind, placebo-controlled, parallel-group trial

Influence of ingestion of eicosapentaenoic acid-rich fish oil on muscle damage and delayed onset muscle soreness following eccentric contractions: a randomized, double-blind, placebo-controlled, parallel-group trial - Influence of eicosapentaenoic acid on muscle damage and delayed onset muscle soreness

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000038003

Enrollment

Registered

2019-09-13

Start date

2019-09-13

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

muscle damage and delayed onset muscle soreness

Interventions

Tested material: EPA-rich fish oil Dosage: 2.4g/day Duration: 4 weeks Tested material: corn oil Dosage: 2.4g/day Duration: 4 weeks

Eligibility

Sex/Gender

Male

Inclusion criteria

Inclusion criteria: Healthy male subjects

Exclusion criteria

Exclusion criteria: Subjects with /resistance training more than five times a week for a year /no resistance training or exercise during over a year /serious liver, kidney, heart, respiratory, endocrine or metabolic diseases/ scheduled for surgery during this study/ administration of regular medication/ regular administration of supplements which affect this study / food allergies/ participation of other clinical trial during this study/ restriction of exercise/ any reason in the opinion of the lead principal investigator not to take part in this study

Design outcomes

Primary

Measure	Time frame
After ingestion of tested materials for 4 weeks, subjects perform eccentric contraction ( ECC ) with elbow flexors. Before and after ECC, 1)Range of motion 2)Maximal isometric contraction torque 3)Muscle soreness measured as a visual analog scale	—

Countries

Japan

Contacts

Public ContactEisuke Ochi

Hosei University Faculty of Bioscience and Applied Chemistry

ochi@hosei.ac.jp042-387-6337

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026