Recurrence-free survival in ultrasonographically defined, low-risk pediatric acute appendicitis with conservative management without antibiotics

Recurrence-free survival in ultrasonographically defined, low-risk pediatric acute appendicitis with conservative management without antibiotics - Recurrence-free survival in ultrasonographically defined, low-risk pediatric acute appendicitis with conservative management without antibiotics

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000037995

Enrollment

200

Registered

2019-09-17

Start date

2019-09-16

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute appendicitis

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Patients presenting to the Emergency Department at Tokyo Metropolitan Childrens Medical Center and receiving the diagnosis of acute appendicitis by a pediatric surgeon 2. Patients with abdominal ultrasonography and meeting criteria (a) and (b) plus (c) or (d) below. (a) Appendiceal outer diameter equal to or greater than 6 mm (b) No identifiable abscess or mass (c) No irregularity in the submucosal layer (d) Irregular submucosal layer with increased blood flow in the appendiceal wall

Exclusion criteria

Exclusion criteria: 1. Antibiotic administration within 72 hours prior to the initial diagnosis of acute appendicitis 2. Previous diagnosis of acute appendicitis 3. Refusal to participate in the study

Design outcomes

Primary

Measure	Time frame
The duration from the diagnosis of initial acute appendicitis to the diagnosis of recurrence	—

Secondary

Measure	Time frame
1. Recurrence rate within one year after the initial diagnosis of the acute appendicitis 2. Recurrence rate within three years after the initial diagnosis of acute appendicitis 3. Mortality rate within one year after the initial diagnosis of acute appendicitis 4. Rate of surgery at following diagnosis of the first recurrence 5. Rate of clinical improvement within one week after the initial diagnosis of acute appendicitis	—

Measure

Time frame

1. Recurrence rate within one year after the initial diagnosis of the acute appendicitis 2. Recurrence rate within three years after the initial diagnosis of acute appendicitis 3. Mortality rate within one year after the initial diagnosis of acute appendicitis 4. Rate of surgery at following diagnosis of the first recurrence 5. Rate of clinical improvement within one week after the initial diagnosis of acute appendicitis

—

Countries

Japan

Contacts

Public ContactQianzhi Wang

Tokyo Metropolitan Children's Medical Center Department of General Pediatrics

kenno_ou@tmhp.jp042-300-5111

Outcome results