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Combined effect of early nutritional therapy and rehabilitation for patients with acute exacerbation of chronic obstruc tive pulmonary disease

Combined effect of early nutritional therapy and rehabilitation for patients with acute exacerbation of chronic obstruc tive pulmonary disease - efficacy of early nutrition and exercise therapy for AE-COPD:ENETAC trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000037984
Enrollment
60
Registered
2019-09-10
Start date
2019-09-10
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

acute exacerbation of chronic obstructive pulmonary disea se

Interventions

nutritional therapy with rehabilitation which started within 72 hours after admission, nutritional therapy is performed. The total energy expenditure is estimated by multiplying the basic energy ex

Sponsors

JCHO Hokkaido Hospital
Lead Sponsor
Kobe university, Graduate school of medicine, the integrated center for mass spectrometry
Collaborator

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: patients with exacerbation of COPD who are hospitalization for treatment.

Exclusion criteria

Exclusion criteria: Patients who have difficulty in walking because of sensory disturbance, musculoskeletal disease and cerebrovascular disease. Patients with malignancy who have not undergone radical treatment. Patients with clinically diagnosed interstitial pneumonia. Patients who take steroids usually before hospitalization. Patients who have difficulty in walking alone because of visual impairment. Patients who require special consideration such as writing for communication because of hearing impairment. Patients who with dementia or delirium before hospitalization, who were not able to evaluate and intervention. Patients who are determined to be inappropriate as research subjects by the investigators.

Design outcomes

Primary

MeasureTime frame
muscle strength of knee extensor (after 2 weeks intervention)

Secondary

MeasureTime frame
Grip strength, 6-minute walking distance, Japanese Cardio vascular Health Study index, Short Physical Performance Battery, Serum total protein, Serum albumin, Geriatric Nutritional Risk Index, Blood lipid mediator

Countries

Japan

Contacts

Public ContactYohei Oyama

JCHO Hokkaido Hospital Department of Rehabilitation

oyama-youhei@hokkaido.jcho.go.jp011-831-5151

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026