Osteoarthritis of the knee
Conditions
Interventions
The exercise contents of the intervention group are a squat, a forward lunge, bilateral leg extension with blood flow restriction and cycle ergometer training. These exercises are performed once or tw
Sponsors
Kobori Orthopedic Clinic
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Japanese males and females 2. between 60 and 79 years old 3. primary knee osteoarthritis 4. radiographic severity classified using Kellgren-Lawrence System was grade 3 to grade 4
Exclusion criteria
Exclusion criteria: 1. patients with serious heart disease, respiratory disease, and diabetes 2. history of neurological disease, and peripheral artery disease 3. patients with abnormalities of blood coagulation and fibrinolysis 4. smoker 5. patients who cannot exercise due to knee pain
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary outcome is quadriceps muscle strength. All patients included in the study are assessed 5 times: tests are performed 6 weeks and 1 week before surgery, 4 days, 1 month and 3 months after surgery. | — |
Secondary
| Measure | Time frame |
|---|---|
| The secondary outcomes are inflammatory response immediately after surgery, knee swelling, knee range of motion, performance test, knee injury and osteoarthritis outcome score (KOOS), and Japanese knee osteoarthritis measure (JKOM). | — |
Countries
Japan
Contacts
Public ContactYusuke Kubo
Kobori Orthopedic Clinic Department of Rehabilitation Medicine
Outcome results
None listed