Prospective observational study of the neurocognition in patients treated with prophylactic cranial irradiation in limited stage small cell lung cancer.

Prospective observational study of the neurocognition in patients treated with prophylactic cranial irradiation in limited stage small cell lung cancer. - LOGIK1901

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000037978

Enrollment

Registered

2019-09-10

Start date

2019-07-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

small-cell lung cancer

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1)Patients who are histologically or cytologically diagnosed as small-cell lung cancer 2)Patients who diagnosed as limited disease 3) Patients treated with radical chemoradiotherapy 4) Patients without brain metastasis after radical chemoradiotherapy 5)Within 28 days after final chemotherapy or radiotherapy irradiation 6)PS 0 -2 7)Patients providing the written informed consent 8)Patients with life expectancy of at least 6 months

Exclusion criteria

Exclusion criteria: 1)Patients with less than or equal to 23 points of MMSE score 2)Any other patients who are regarded as unsuitable for this study by the principal investigator or sub-investigators. 3)Patients who refuse the participation in the study 4)Patients who did not respond to chemoradiation 5)Patients who cannot answer the questionnaire and MMSE 6)Patients treated with operation for LD-SCLC

Design outcomes

Primary

Measure	Time frame
Change in MMSE score at 24 months from the enrollment	—

Countries

Japan

Contacts

Public ContactYoshiro Nakahara

Kitasato University School of Medicine Department of Respiratory Medicine

md100062@kitasato-u.ac.jp042-778-8506

Outcome results