Healthy Adults
Conditions
Interventions
Sugar load*1 at the time of screening and Sugar load after taking red clover extract 1.91g on the test day before intake. In addition, take red clover extract 1.91g every day for 8 weeks, once a day
Sponsors
Healthcare Systems Co., Ltd.
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1.Persons who received a sufficient explanation of the purpose and contents of the exam, have the capacity to consent, applied with free will with sufficient understanding, and agreed to participate with a written document 2.Healthy Japanese over 20 years old and under 65 at the time of consent acquisition 3.Those whose BMI less than 25 at the time of screening 4.Those whose blood glucose concentration is less than 126 mg per dL at the time of screening 5.Those with occasional blood glucose levels of less than 200 mg per dL at screening 6.Those whose blood HbA1c is less than 6.5% at the time of screening 7.Those who apply to 6 and are top 40 of numerical value of HbA1c.
Exclusion criteria
Exclusion criteria: 1.Those who have a chronic disease and are undergoing medication, those with a serious disease history 2.Those who are allergic to the test food 3.Those who regularly use medicines, specific insurance foods, health foods, etc. that may affect blood glucose levels 4.Those who have participated in other tests within the first month before the start of the exam, or who are planning to participate in other exams after this exam consent 5.Those who are judged ineligible at the discretion of the examining supervisor and research leader 6.Those who are breast-feeding, pregnant, and are planning or hoping pregnancy during the exam
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| HbA1c 8 weeks after continuous intake Time course of blood glucose concentration changes before and after a single ingesting(C,Cmax,Tmax,delta AUC) *Measure at before ingestion and 30, 60, 90, and 120 minutes after ingestion. | — |
Secondary
| Measure | Time frame |
|---|---|
| Time course of blood insulin concentration changes before and after a single ingesting(C,Cmax,Tmax,delta AUC) *Measure at just before ingestion and 30, 60, 90, and 120 minutes after ingestion. fasting blood glucose level 8 weeks after continuous intake fasting blood insulin level 8 weeks after continuous intake Physical examination (body height, weight, BMI) | — |
Countries
Japan
Contacts
Public ContactTakamasa Masuda
Healthcare Systems Co., Ltd. Research and Development Department
Outcome results
None listed