Genome-wide analysis of advanced lung cancer cases that showed marked response to chemotherapy resulting in a treatment-free long-term remission

Genome-wide analysis of advanced lung cancer cases that showed marked response to chemotherapy resulting in a treatment-free long-term remission - Genome-wide analysis of advanced lung cancer cases that showed marked response to chemotherapy resulting in a treatment-free long-term remission

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000037822

Enrollment

Registered

2019-08-28

Start date

2019-08-28

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lung cancer, Mesothelioma

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Stage IV lung cancer or mesothelioma with pathological confirmation 2. Age 20 or older 3. Lung cancer or mesothelioma in remission (complete remission or partial remission) that is achieved by chemotherapy and maintained without any cancer treatment for 2 years or longer after the last dose of chemotherapy 4. Available tumor tissue before chemotherapy for DNA and protein analysis 5. Available peripheral blood sample for DNA extraction as a non-cancerous reference 6. Written informed consent

Exclusion criteria

Exclusion criteria: 1. Active double cancer (patients with treatment-free and disease-free state for 3 years or longer after a curative treatment are eligible) 2. Unsuitable to enter this study judged by an attending physician

Design outcomes

Primary

Measure	Time frame
Exploratory assessment of somatic alterations in advanced lung cancer related to marked response to chemotherapy and treatment-free long-term remission	—

Countries

Japan

Contacts

Public ContactAKIHITO KUBO

Aichi Medical University School of Medicine Division of Respiratory Medicine and Allergology

kuboa@aichi-med-u.ac.jp81-561-62-3311

Outcome results