healthy volunteer
Conditions
Interventions
Injection of 18F-fluorodeoxyglucose (FDG)
to give exercise load (and resting)
Sponsors
Tohoku Univeristy Cyclotron and Radioisotope Center
Fukushima Prefectural Medical University
Eligibility
Sex/Gender
Male
Inclusion criteria
Inclusion criteria: 1) healthy adult men 2) Performance Status (grade0) 3) 3-a) 20 to 40 years old with exercise habits 3-b) 20 to 40 years old without exercise habits 3-c) 65 to 80 years old with exercise habits 3-d) 65 to 80 years old without exercise habits 4) right handed
Exclusion criteria
Exclusion criteria: 1) Person who has abnormality in his brain strctural images 2) Person who has contra-indications to MR examinations 3) Person who has allergies to drugs and foods, etc. (including hypersensitivity to alcohol) 4) Person who has once become ill following injection and infusion. 5) Person who has had experiences of serving as a research volunteer of certain clinical studies in which radiation exposures are given to the subjects (such as other PET studies). 6) Person without minimal exercise ability (to be tested before enrollment) 7) Person with regular medication 8) Person who is diabetic.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| *Standardized Uptake Value and SUV change measured by FDG-PET in brain and muscles. *Metabolite concentration and its change measured by MRS in brain and muscles. | — |
Countries
Japan
Contacts
Public ContactManabu TASHIRO
Tohoku University Cyclotron and Radioisotope Center
Outcome results
None listed