Intravenous Paracetamol vs Tramadol for pain management in patients with Acute Pancreatitis

Intravenous Paracetamol vs Tramadol for pain management in patients with Acute Pancreatitis - PCM vs Tramadol in Pain Management in AP

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000037790

Enrollment

Registered

2019-08-24

Start date

2019-05-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pain Management in Acute Pancreatitis

Interventions

Patients will be given IV Paracetamol1gm in 100 ml NS over 4-5 min infusion thrice daily and pain will be assessed by using VAS scores after 24 hours. Patients will be given IV Tramadol 50 mg in 100 m

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1)Adult patients (>18 years age) 2)Diagnosis of Acute Pancreatitis with abdominal pain

Exclusion criteria

Exclusion criteria: 1)Severe hepatic impairment 2)Severe renal impairment ( CrCl < 30ml/min) 3)Ongoing treatment with NSAIDs (within 24 h) 4)History of allergy to paracetamol, and/or tramadol

Design outcomes

Primary

Measure	Time frame
To compare the efficacy of Paracetamol vs Tramadol in pain management of Acute Pancreatitis.	—

Secondary

Measure	Time frame
1)To determine number of patients with drug related adverse events in paracetamol vs tramadol arm 2)To determine causes of acute pancreatitis 3)To analyze the incidence of severity of acute pancreatitis as per the revised Atlanta Classification 4)To determine impact of two drugs on duration of hospital stay	—

Countries

Asia(except Japan)

Contacts

Public ContactRoshan Shrestha

National Academy of Medical Sciences, Bir Hospital Gastroenterology Unit

roshan_sth@hotmail.com9779851136352

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026