Effect of exercise therapy combined with hyperthermia on blood BDNF concentration in healthy young men

Effect of exercise therapy combined with hyperthermia on blood BDNF concentration in healthy young men - Effect of exercise therapy combined with hyperthermia on blood BDNF concentration in healthy young men

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000037781

Enrollment

Registered

2019-08-23

Start date

2019-09-16

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

young healthy men

Interventions

Bicycle ergometer (60% of maximal oxygen uptake) 15 minutes in subjugated water at 40&#39

C 40&#39

C, subjugated water 15 minutes

Eligibility

Sex/Gender

Male

Inclusion criteria

Inclusion criteria: 1.20-30age 2.a person able to communicate (No cognitive or higher brain dysfunction) 3.Those who wish to participate voluntarily

Exclusion criteria

Exclusion criteria: Persons with diabetes mellitus, heart disease, chronic inflammatory disease, or skin disease.

Design outcomes

Primary

Measure	Time frame
Serum and plasma brain-derived neurotrophic factor (BDNF; brain-derived neurotrophic factor) immediately after 15 minutes of warm bath exercise therapy	—

Secondary

Measure	Time frame
Plasma cortisol, lactic acid, Serum S 100 .BETA., neuron-specific enolase (NSE; neuron-specificenolase), Irisin, P selectin (CD 62 P), CBC (CBC; complete blood count), central temperature (esophageal temperature), blood pressure, heart rate, perceived exertion (Borg Scale), water temperature	—

Countries

Japan

Contacts

Public ContactOhko Hiroshi

Wakayama Medical University rehabilitation medicine

ohko-h@seijoh-u.ac.jp073-441-0664

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026