Parkinson'
Conditions
Interventions
mindfulness meditation
Sponsors
Wakayama Medical University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Clinically Established or Probable PD diagnosed by MDS clinical diagnostic criteria for Parkinson's disease 2. Over 20 years old 3. Patients who can obtain informed consent
Exclusion criteria
Exclusion criteria: 1. Severe dementia or hallucination/delusion 2. Severe hearing loss or severe visual impairment 3. Disturbance in consciousness 4. Participating in other intervention trials 5. Changed antiparkinsonian drugs within 28 days before enrollment 6. New antipsychotics or antidepressants within 84 days before enrollment 7. Symptomatic stroke or encephalitis within 84 days before enrollment 8. Daily meditation or yoga
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The BIS-11 (Barratt Impulsiveness Scale) score reduction effect of 8 weeks of mindfulness meditation. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Questionnaires for clinical symptoms (week 0, week 2 and week 8) 1) Impulsivity scale: BIS-11 2) Impulsive control disorder scale: QUIP-RS-J 3) QOL scale for Parkinson's disease: PDQ-8 4) Mindfulness scale: MAAS 5) Depression and apathy: HADS 6) Mental symptoms and care burden: NPI-Q 2. Motor symptoms in Parkinson's disease (week 0, week 8) 1) MDS-UPDRS part3 2) Hohen-Yahr score 3. Cognitive function (week 0) 1) Mini-Mental State Examination (MMSE) 4. MRI (week 0, week 8) 1) Resting-state functional MRI 2) Voxel-based morphometry 3) T1w / T2w ratio image | — |
Countries
Japan
Contacts
Public ContactJinsoo Koh
Wakayama Medical University Department of Neurology
Outcome results
None listed