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Exploratory clinical study on the prevention effect of Docetaxel-induced peripheral neuropathy by compression therapy using surgical gloves and lower limb stockings

Exploratory clinical study on the prevention effect of Docetaxel-induced peripheral neuropathy by compression therapy using surgical gloves and lower limb stockings - Glove stocking study for Decetaxel -induced peripheral neuropathy

Status
Recruiting
Phases
Phase 2
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000037761
Enrollment
75
Registered
2019-08-21
Start date
2019-05-27
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Prostate cancer

Interventions

:Double surgical gloves that are one size smaller than the appropriate size, wear them 30 minutes before docetaxel administration, and remove the gloves 30 minutes after docetaxel administration. :Ap

Sponsors

Kagawa university hospital
Lead Sponsor

Eligibility

Sex/Gender
Male

Inclusion criteria

Inclusion criteria: 1) Prostate cancer patients with docetaxel therapy 2) Patients who are over 20 years old and who have obtained informed consent

Exclusion criteria

Exclusion criteria: 1) Patients with peripheral neuropathy at the start of the study 2) Patients who have received medication that may cause peripheral neuropathy in the past. 3) Other patients who are judged inappropriate by the research doctor

Design outcomes

Primary

MeasureTime frame
Presence of peripheral neuropathy at the end of 10 courses Grade 1 or higher is judged to be peripheral neuropathy, and Grade 0 or higher is judged to be no peripheral neuropathy based on the CTCAE ver 5.0.

Secondary

MeasureTime frame
Changes in the nails at the end of the 10 courses Based on the CTCAE ver 5.0, the "Peripheral Nerve Damage and Nail Questionnaire" is used to evaluate Grade 1 or higher as nail damage and Grade 0 as no nail damage.

Countries

Japan

Contacts

Public ContactTakuma Kato

Kagawa university Department of Urology, faculty of medicine

takuma_k@med.kagawa-u.ac.jp087-891-2202

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026