None listed
Conditions
Interventions
Consume test food, one package a day for 10 weeks. Conduct health check, QOL questionnaire and stool analysis at 0, 4 and 8 weeks, skin tests at 0 and 8 weeks, blood tests at 8 weeks after start of th
Sponsors
CPCC Company Limited
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: 1) Females aged 30 to 49 years old. 2)Subjects who are before menopause and have stable menstrual period within 28 days to 35 days. 3) Subjects who are aware to bad condition of their skin. 4) Subjects who have no habit to consume health food which have intestinal action such as dietary fiber reinforced foods, multigrain rice, oligo sugar. 5) Subjects who have no habit to consume lactic acid bacteria supplements, bifidobacterium supplements, and/or yeast supplements. 6) Subjects who show understanding of the study procedures and agreement with participating the study by written informed consent prior to the study.
Exclusion criteria
Exclusion criteria: Subjects who 1)have habit to consume yogurt more than 3 days a week. 2)have habit to consume beverages include lactic acid bacteria and/or bifidobacteria more than 2 days a week. 3)have habit to consume vitamin supplements more than 3 days a week. 4)regularly use gastrointestinal drugs or female hormone. 5)have taken antibiotics within a month. 6)are currently being treated or who plan to be treated for pollen allergy. 7)repeat constipation and diarrhea. 8)declared their defecate habit as >= 3 times and/or <= 9 times in a week. 9)have severe past and/or current medical history. 10)are being treated or have medical histories uterine fibroid and/or ovarian cyst. 11)are pregnant or are lactating. 12)have allergy to medicine and/or food. 13)are atopic dermatitis, contact dermatitis and/or skin hypersensitivity. 14)have rough skin because of pollen allergy. 15)have birthmark, scar and/or acne on the part of measurement. 16)have excess suntan and/or who stay outside long time. 17)plan to go traveling abroad and/or to go swimming in the sea during this test period. 18)are receiving special care of face and/or arm in the service. 19)have excess irregular meal cycle and/or have irregular life rhythm. 20)are excessive smoker and/or heavy drinkers of alcohol. 21)are participating, who have participated within 4 weeks and/or who plan to participate after informed consent, in other clinical test. 22)donated over 200mL blood and/or blood components within a month. 23)donated over 400mL blood within the last 4 months. 24)will be collected over 800mL blood and/or blood components when the sampling amounts within the last 12 months are adding to the planned sampling amounts of this study. 25)Others they have been determined ineligible by investigator.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| *Moisture content of the horny layer *Transepidermal water loss | — |
Secondary
| Measure | Time frame |
|---|---|
| *QOL questionnaire *Stool tests (Physical and chemical analysis, Microbiota of gut) *Days of defecation *Defecation frequency *Fecal properties *Urine test * Incidence of adverse events and of side effects | — |
Countries
Japan
Contacts
Public ContactMasanori Numa
CPCC Company Limited Planning & Sales Department
Outcome results
None listed