Evaluation of the anti-wrinkle effect of a intradermal thumbtack type micro-needle: a randomized, double-blind, placebo-controlled trial

Evaluation of the anti-wrinkle effect of a intradermal thumbtack type micro-needle: a randomized, double-blind, placebo-controlled trial - Evaluation of the anti-wrinkle effect of a intradermal thumbtack type micro-needle

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000037692

Enrollment

Registered

2019-08-16

Start date

2019-08-15

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

wrinkle

Interventions

Skincare with scattered needling method using a intradermal thumbtack type micro-needle (pyonex 0.3mm) Skincare with scattered needling method using a placebo-needle (PY placebo)

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Healthy men and women with wrinkles (1 to 3 wrinkle grades). Without an exclusion criterion, and a person who can comply with the prohibitions. 1. Take skincare treatments that affect the test site during the study participation period. 2. Ingest or use external preparations, medicines and supplements intended to improve wrinkles during study participation period. 3. It is exposed to excessive ultraviolet rays, such as swimming, mountain climbing, sunbathing, exercise outdoors.

Exclusion criteria

Exclusion criteria: 1. Those who have a history of allergies to cosmetics and metals. 2. Those who are receiving "hormone replacement therapy". 3. Those who are pregnant and nursing. 4. Those who have experience in cosmetic care to affect the test site. 5. Those who deemed inappropriate for this study by the investigator.

Design outcomes

Primary

Measure	Time frame
evaluation of wrinkles (JCSS)	—

Countries

Japan

Contacts

Public ContactShogo Miyazaki

Teikyo Heisei University Faculty of Health Care

s.miyazaki@thu.ac.jp03-5843-3111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026