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Study on the relationship between the breath acetaldehyde/ethanol ratio and the risk of Head and Neck/Esophageal cancer

Study on the relationship between the breath acetaldehyde/ethanol ratio and the risk of Head and Neck/Esophageal cancer - Breath AERO-E study

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
JPRN
Registry ID
JPRN-UMIN000037677
Enrollment
360
Registered
2019-08-13
Start date
2019-10-13
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Esophageal cancer Head and Neck cancer

Interventions

None listed

Sponsors

Kyoto University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1)diagnosed with head and neck cancer, esophageal cancer, gastric cancer, or suspected of having the disease, and scheduled to undergo endoscopy (iodine staining) for detailed examination and follow up after treatment 2)over 20 years old 3)clinical laboratory values meet the following standards AST, ALT, GGTP Less than twice the facility standard upper limit of the research institution 4)obtain written consent from the subject

Exclusion criteria

Exclusion criteria: 1)allergic to alcohol 2)allergic to iodine 3)pregnant or may be pregnant or breastfeeding 4)serious complications (such as chronic obstructive pulmonary disease that requires oxygen inhalation, pulmonary fibrosis, symptomatic heart failure) 5)history of bronchial asthma, drug allergies, etc. 6)history of cancer treatment other than endoscopic treatment 7)history of resection of the esophagus, stomach, liver, pancreas (excluding endoscopic treatment) 8)stricture in esophagus 9)judged inappropriate by the attending physician

Design outcomes

Primary

MeasureTime frame
Correlation between A/E ratio in expired air and Lugol-voiding lesions grade

Countries

Japan

Contacts

Public ContactYuki Kondo

Graduate school of Medicine, Kyoto University Department of Therapeutic Oncology

ykondo@kuhp.kyoto-u.ac.jp075-751-4592

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026