ear disease
Conditions
Interventions
measurement of plasma orexin-A (4 times)
measurement of plasma norepinephrine and epinephrine (4times)
Sponsors
Department of Anesthesiology and Intensive care, Faculty of Medicine, University of Miyazaki.
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients undergoing ear surgery at the Miyazaki University Hospital, Miyazaki, Japan between August 2015 and September 2016 were recruited. Written informed consent was obtained from all patients. Forty-seven patients with ASA physical state 1 or 2 undergoing ear surgery under total intravenous anesthesia (TIVA) or sevoflurane anesthesia (SEV) were enrolled.
Exclusion criteria
Exclusion criteria: Patients were excluded who had used analgesics, sedatives, or antidepressants within 72 h prior to surgery; had a history of obstructive sleep apnea syndrome, chronic obstructive pulmonary disease, diabetes mellitus, endocrine disorder, or neurological disease; had a hepatic, renal, or psychological disorder; whose operation time was < 2 hours or > 5 hours; were < 20 or > 70 years old, or had a BMI < 18.5 or > 25.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Compare the plasma OXA levels in patients undergoing ear surgery with total intravenous anesthesia and inhalational aneshesia. | — |
Secondary
| Measure | Time frame |
|---|---|
| To compare the emergence time from anesthesia with total intravenous anesthesia and inhalational aneshesia. | — |
Countries
Japan
Contacts
Public ContactTetsuro Shirasaka
Faculty of Medicine, University of Miyazaki Department of Anesthesiology and Intensive care
Outcome results
None listed