Stable vitiligo
Conditions
Interventions
Sponsors
Osaka University Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Men and women aged over 20 years old with a diagonosis of stable vitiligo who visited the department of dermatology Osaka University Hospital and who signed a written informed consent by themselves after receiving the explanation of clinical study.
Exclusion criteria
Exclusion criteria: Apparently unstable patients defined as new areas of depigmentation or enlarging areas of depigmentation within the last 12 months. Patients with treatment of steroid, active vitamin D3, calcineurin inhibitor and light radiation therapy within the 4 weeks befor registration. History of keloidal scars and presence of Koebner's phenomenon Patients with allergies to antibiotics and local anaesthetics Patients with tape rash Pregnant women, lactating women and patients who deaire pregnancy during clinical studies. Positive serology of Hepatitis B and C, HIV, HTLV-1 Patients who are participating in other clinical studies including interventions or non-interventions such as observation studies. Investigators judge the patiens should not paticipate in the study for any reason
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Evaluation of repigmentation rate of cell transplantation area (test site), suction blister transplantation area (comparison site), non-treated area (control site) by calculating the area of images taken by digital camera.Photographs are taken before, 3 months after and 6 months after the operation. Observation of the wound areas of donor site, test site, comparison site and control site as a safety evaluation. | — |
Secondary
| Measure | Time frame |
|---|---|
| Evaluation of color matching (melanin and hemoglobin) on the test site, comparison site, control site and peripheral healthy site by the Mexameter. Incidence of adverse effects like infection, scarring and hemorrhoids resulting from the regenerative medicine as a safety evaluation. Color matching and safety evaluation are performed before, 3 months after and 6 months after the operation. | — |
Countries
Japan
Contacts
Public ContactAtsushi Tanemura
Osaka University Graduate School of Medicine Development of Dermatology
Outcome results
None listed