A Retrospective Analysis on Relationship between Autoantibody Profile of Rheumatoid Arthritis Patients Registered in Tsurumai Biologics Communication Registry (TBCR) and Effects/Safety of Abatacept

A Retrospective Analysis on Relationship between Autoantibody Profile of Rheumatoid Arthritis Patients Registered in Tsurumai Biologics Communication Registry (TBCR) and Effects/Safety of Abatacept - Relationship between autoantibody profile of rheumatoid arthritis patients and clinical outcomes of abatacept

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000037572

Enrollment

400

Registered

2019-08-01

Start date

2017-01-14

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

rheumatoid arthritis

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: I) Rheumatoid arthritis patients that that met the 2010 ACR/EULAR RA classification criteria ii) Patients treated with abatacept under patients' doctor's decision and followed for at least 1 year. iii) Patients with data of anti-CCP antibody titer measured before starting abatacept treatment.

Exclusion criteria

Exclusion criteria: Patients who were considered not to be eligible for this study.

Design outcomes

Primary

Measure	Time frame
Proportion of patients that achieved SDAI remission criteria at 52 weeks in rheumatoid arthritis patients with and without ACPA positivity treated with abatacept.	—

Secondary

Measure	Time frame
Progression of joint destruction in rheumatoid arthritis patients with and without ACPA positivity treated with abatacept Safety profile of abatacept treatment in rheumatoid arthritis patients with and without pulmonary comorbidity.	—

Countries

Japan

Contacts

Public ContactNobunori Takahashi

Nagoya University Hospital Orthopaedic Surgery

nobunori@med.nagoya-u.ac.jp052-741-2111

Outcome results