atrial fibrillation
Conditions
Interventions
In addition to pulmonary vein isolation, mapping-guided ablation is performed.
Pulmonary vein isolation is performed.
Sponsors
Tokyo Medical and Dental University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Symptomatic persistent or longstanding persistent atrial fibrillation. 2) Documentation of AF 3-month before the enrollment of the study. 3) Documentation of sinus rhythm within 3-year before the enrollment of the study. 4) Refractory or intolerent to antiarrhythmic drugs.
Exclusion criteria
Exclusion criteria: 1) Sinus rhythm from 3-month before the enrollment of the study to the beginning of the ablation procedure. 2) Prior catheter ablation for atrial fibrillation or uncommon atrial flutter. 3) Prior surgical Maze procedure. 4) Patients in whom cardiac implantable electronic devices were implanted. 5) Patients who were taking aimodarone within 1-year from the enrollment of the study. 6) Untreated thyroild dysfunction. 7) End-stage renal disease (eGFR<15 or requirement of hemodialysis).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Freedom from atrial fibrillation, atrial flutter or atrial tachycardia after a single catheter ablation procedure. | — |
Secondary
| Measure | Time frame |
|---|---|
| Freedom from atrial fibrillation, atrial flutter or atrial tachycardia after multiple catheter ablation procedures. Freedom from persistent atrial fibrillation, persistent atrial flutter or persistent atrial tachycardia after a single catheter ablation procedure. | — |
Countries
Japan
Contacts
Public ContactYoshihide Takahashi
Tokyo Medical and Dental Unive Department of Advanced Research
Outcome results
None listed