None(Healthy subjects)
Conditions
Interventions
single ingestion of the natural extract - washout period(6 days or more)- single ingestion of the processed extract
single ingestion of the processed extract - washout period(6 days or more)- single i
Sponsors
Shiba Palace Clinic
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1)Japanese males and females from 20 to 59 years old when the consent is obtained 2)Healthy participants 3)Subjects who can be collected their blood multiple times(6 times per day) 4)Subjects with the normal fasting serum triglyceride value and LDL-cholesterol value
Exclusion criteria
Exclusion criteria: 1)Subjects who are pregnant. 2)Smokers. 3)Subjects with a history of cancers or gastrointestinal diseases (except appendicitis). 4)Subjects who take the medicine related to lipids absorption. 5)Subjects who take the same medicine habitually. 6)Subjects with diseases such as autoimmune diseases, chronic inflammatory diseases and the diabetes mellitus. 7)Subjects who take the excessive alcohol(equivalent alcohol to 633 mL of beer or more at least 5 days a week). 8)Subjects who participate in another clinical trial. 9)Subjects with serious anemia. 10)Subjects who donated 200 mL or 400 mL whole blood or were transfused within 3 months before the screening.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Comparison of the serum lycopene concentration at each sampling point and AUC 0-12h of lycopene after intake of processed tomato extract with normal tomato extract(The analysis of actual measured values and the amount of changes values from baseline after the loading tomato extracts). | — |
Countries
Japan
Contacts
Public ContactYoshiyuki Shirakura
FUJIFILM Healthcare Laboratory Co., Ltd. Department of Supplement product management
Outcome results
None listed