The Effects of Benzodiazepine and Orexin Receptor Antagonist on Cognitive Function Revealed by Auditory Event-related Potentials

The Effects of Benzodiazepine and Orexin Receptor Antagonist on Cognitive Function Revealed by Auditory Event-related Potentials - ERPs reflect BZ and suvorexant effects on cognition

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000037363

Enrollment

Registered

2019-07-15

Start date

2016-02-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Insomnia

Interventions

Receiving suvorexant 20 mg Receiving lormetazepam 2 mg Receiving placebo

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Healthy participants aged 20 years and older

Exclusion criteria

Exclusion criteria: History of mental illness and neurological disorder

Design outcomes

Primary

Measure	Time frame
Individual mean amplitudes of mismatch negativity (MMN) and P300 1 day after oral administration of lormetazapam and suvorexant.	—

Countries

Japan

Contacts

Public ContactTetsuya Shiga

Fukushima Medical University Department of Neuropsychiatry

tetsuya3@fmu.ac.jp024-547-1331

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026