Effect of heat and moisture exchanger filter on end-tidal carbon dioxide measurement with mainstream capnography in critically ill patients: A single-center prospective observational study

Effect of heat and moisture exchanger filter on end-tidal carbon dioxide measurement with mainstream capnography in critically ill patients: A single-center prospective observational study - Effect of heat and moisture exchanger filter on end-tidal carbon dioxide measurement with mainstream capnography in critically ill patients: A single-center prospective observational study

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000037317

Enrollment

Registered

2019-07-16

Start date

2019-07-16

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Adult critically ill patients receiving mechanical ventilation

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Adult patients (20 years or older) admitted to the intensive care unit and received mechanical ventilation through orotracheal or tracheostomy tube. 2. The respiratory circuit was humidified with heat and moisture exchanger filter. 3. Patients with arterial line.

Exclusion criteria

Exclusion criteria: 1.Pregnancy 2.Patients previously enrolled in this study 3.Refusal of study participation 4.Patients do not meet the safety criteria. If patients have any of the following physiological signs, the patients are judged not meeting the safety criteria. Ventilator settings -PEEP 10 cmH2O or more -Fraction of inspired oxygen 0.6 or more Heart rate -below 40 bpm, 130 bpm or more Mean arterial pressure -below 60 mm Hg, 110 mm Hg or more Oxygen saturation -below 90% Respiratory rate -40 breaths per minute or more Body temperature -below 36 degrees Celsius, 38.5 degrees Celsius or more 5. Treating physicians judged that study participation of the patient is inappropriate.

Design outcomes

Primary

Measure	Time frame
Absolute differences between arterial partial pressure of carbon dioxide (PaCO2) and EtCO2. Delta EtCO2 of ventilator side= absolute differences between PaCO2 and EtCO2 measured on the ventilator side of the HME filter. Delta EtCO2 of patient side= absolute differences between PaCO2 and EtCO2 measured on the patient side of the HME filter.	—

Countries

Japan

Contacts

Public ContactSatoshi Tamashiro

Okinawa Chubu Hospital Department of Clinical engineering

tamashiro_satoshi@hosp.pref.okinawa.jp098-973-4111

Outcome results