Healthy adults
Conditions
Interventions
Daily intake of high-dose test food for 4 weeks
Daily intake of low-dose test food for 4 weeks
Daily intake of placebo food for 4 weeks
Sponsors
Shiba Palace Clinic
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: 1) Healthy Japanese females aged 30 to 49 years old 2) Subjects who have less habit of eating yogurt (2 times a week or less) 3) Subjects who have less habit of drinking lactic acid bacteria beverage (once a week or less) 4) Subjects who have no habit of taking in fiber-fortified foods, oligosaccharides or lactic acid bacteria Yeast supplements 5) Subjects with defecation frequency 4 to 8 times per week 6) Subjects with hard to normal form of stool (Bristol Stool Scale 2 to 4) 7) Subjects who do not alternate constipation and diarrhea 8) Subjects who can collect their own stool specimens and keep them in their own freezer at home until submission 9) Subjects who have periodic menstruation 10) Subjects with BMI less than 25
Exclusion criteria
Exclusion criteria: 1) Subjects who participate in other clinical trials 2) Subjects who are pregnant, lactating or possibly pregnant 3) Subjects with menopause 4) Subjects with tendency of diarrhea or loose stool 5) Subjects who regularly use antiflatulents, stomach medicines, gastrointestinal drugs, laxatives or female hormones
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Intestinal bacterial flora | — |
Secondary
| Measure | Time frame |
|---|---|
| Stool composition Questionnaire on defecation(distention, exhaust gas amount, defecation frequency, defecation pain, defecation quantity, defecation feeling, stool form, stool smell) | — |
Countries
Japan
Contacts
Public ContactMiwa Kaneko
SOUKEN Co., Ltd Management Division
Outcome results
None listed