Relationship between protein intake and muscle strength and muscle mass in elderly chronic kidney disease patients

Prospective observational study on association of dietary protein intake with changes in muscle strength and skeletal muscle mass, in elderly chronic kidney disease (CKD) patients - Prospective observational study on association of dietary protein intake with changes in muscle strength and skeletal muscle mass, in elderly chronic kidney disease (CKD) patients

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000037312

Enrollment

150

Registered

2019-07-09

Start date

2018-03-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Elderly nondialysis chronic kidney disease patients (stage3b-4)

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: CKD patients who had been treated in Tokyo Medical College Hachioji Medical Center at least of 6 months before enrolment, and who had been optimized blood pressure and serum electrolyte, and who reserved life instruction including exercise. Patients who received explanation for purpose and contents of this study, and who agreed by free will. Patients who can go to hospital for two years.

Exclusion criteria

Exclusion criteria: Patients who are instructed to rest. Patients with serious circulatory and respiratory disease. Patients who are treating musculoskeletal disease. Patients who have asymmetric lower limbs atrophy. Patients who require walking aids when moving due to motor failure. Patients whose body protein catabolism has been renewed by steroid therapy, burns, etc. Patients with chronic inflammatory disease. Diabetic patients with HbA1c 7.0 % or higher. Patients with proteinuria 3.5g/day or higher Patients with cardiac pacemaker

Design outcomes

Primary

Measure	Time frame
To clarify the association between dietary protein intake and percent change in baseline muscle strength and skeletal muscle mass over two years, in elderly CKD patients.	—

Secondary

Measure	Time frame
To clarify the association between dietary protein intake and factors affecting muscle mass and muscle strength (serum amino acid concentration, acid-base balance, serum vitamin D concentration)	—

Countries

Japan

Contacts

Public ContactNoriko Yoshikawa

Tokyo Medical College Hachiouji medical Center Department of Nephrology and Blood Purification, Kidney Disease Center

ionori@tokyo-med.ac.jp042-665-5611

Outcome results