A Comparison between Diagnostic Tests for Primary Aldosteronism

A Comparison between Confirmatory Tests for the Diagnosis of Primary Aldosteronism - PA Confirmatory Tests Comparison

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000037304

Enrollment

200

Registered

2019-07-29

Start date

2017-08-11

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Primary Aldosteronism

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: (1) patients for whom at least two of the CCT, SIT, FUP, and oral salt-loading test were performed, (2) patients who did not refuse to be included in the study upon information disclosure of the study on the Web site of Shizuoka General Hospital.

Exclusion criteria

Exclusion criteria: (1) patients for whom less than two of the confirmatory tests were performed, (2) patients who refused to be included in the study upon information disclosure of the study.

Design outcomes

Primary

Measure	Time frame
Comparisons among post-CCT aldosoterone/renin ratio (ARR), plasma aldosterone concentration (PAC), post/pre-CCT PAC ratio, post-FUP plasma renin activitiy (PRA), post-SIT PAC, and post-OST urinary aldosterone excretion.	—

Secondary

Measure	Time frame
Concordance among confirmatory test results. Adverse events in each confirmatory test. Clinical characteristics of test-positive patients among confirmatory tests.	—

Countries

Japan

Contacts

Public ContactNaohisa Tamura

Shizuoka General Hospital Research Support Center

naohisa-tamura@i.shizuoka-pho.jp054-247-6111

Outcome results