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Study on EGFR tyrosine kinase inhibitor drug Osimertinib resistance in EGFR mutant NSCLC for analysis of immunohistochemistory of tumor tissues.

Study on EGFR tyrosine kinase inhibitor drug Osimertinib resistance in EGFR mutant NSCLC for analysis of immunohistochemistory of tumor tissues. - Study on Osimertinib resistance mechanism

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
JPRN
Registry ID
JPRN-UMIN000037294
Enrollment
30
Registered
2019-07-06
Start date
2019-07-06
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lung cancer

Interventions

None listed

Sponsors

Juntendo University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1)Pathologically diagnosed with non-small cell lung cancer 2)Harboring EGFR mutation 3)Prior treatment history with Osimertinib 4)Adequate histological sample after resistance to Osimertinib 5)Provided informed consent

Exclusion criteria

Exclusion criteria: None

Design outcomes

Primary

MeasureTime frame
Novel resistant mechanism to Osimertinib

Countries

Japan,North America

Contacts

Public ContactKeita Miura

Juntendo University Respiratory Medicine

k-miura@juntendo.ac.jp03-5802-1063

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026