Chronic constipation
Conditions
Interventions
None listed
Sponsors
Kunimoto Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Patients with 65 years or older 2. Patients with chronic constipation who must include 2 or more the following 6 items a. Straining during more than one-fourth of defecations b. Lumpy or hard stools (BSFS 1or 2) more than one-fourth of defecations c. Sensation of incomplete evacuation more than one-fourth of defecations d.Sensation of anorectal obstruction/blockage more than one-fourth of defecations e. Manual maneuvers to facilitate more than one fourth of defecations f. Fewer than 3 spontaneous bowel movements per week 3. Patients who starts Elobixibat administration from April 19, 2018 to March 31, 2019 (including concomitant use with other constipation drugs)
Exclusion criteria
Exclusion criteria: 1. Patients who had a history of hypersensitivity of elobixibat 2. Patients who are confirmed or suspected intestinal obstruction due to tumor, hernia etc. 3. Patients who are suspected constipation due to organic disease 4. Patients whose physicians judged that administration of elobixibat was inappropriate
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Comparison of CSS total score between baseline and at weeks 2 of administration | — |
Secondary
| Measure | Time frame |
|---|---|
| Comparison of CSS sub score sbetween baseline and at weeks 2 of administration Comparison of Bristol Stool Form Scale (BSFS) between baseline and at weeks 2 of administration etc. | — |
Countries
Japan
Contacts
Public ContactAbe Tatsuya
Kunimoto Hospital Director
Outcome results
None listed