Effects of the Combined Exercise and Game-based Cognitive Training on cancer therapy-related cognitive impairment in patients with breast cancer: Mixed-methods study in the United States and Japan.

Effects of the Combined Exercise and Game-based Cognitive Training on cancer therapy-related cognitive impairment in patients with breast cancer: Mixed-methods study in the United States and Japan. - Effects of the Combined Exercise and Game-based Cognitive Training on cancer therapy-related cognitive impairment in patients with breast cancer: Mixed-methods study in the United States and Japan.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000037187

Enrollment

120

Registered

2019-07-01

Start date

2019-07-01

Completion date

Unknown

Last updated

2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Breast Cancer

Interventions

Intervention group: Combined Exercise and Game-based Cognitive Training Frequency: Participants will be asked to complete the Combined Exercise and Game-based Cognitive Training exercise sessions th

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: (1) women diagnosed with stage I- III breast cancer (2) >/=20 years old, </=75 years old (3) within 6 months to 5 years after completion of chemotherapy; current adjuvant anti-estrogen therapy allowed regardless of other therapies received; current anti-HER-2 therapy allowed. (4) reporting symptoms of cognitive changes (5)a Mini-Mental State Examination (MMSE) score of =>24 (6) ECOG (Eastern Cooperative Oncology Group) Performance Status is 0 or 1 (7) understood the disease and treatment (8) able to read and speak English or Japanese (9) permission of recording an interview data (10) Consent to participate in the study with consent form

Exclusion criteria

Exclusion criteria: (1) recurrence (2) Sequelae of treatment for breast cancer (eg: restricted movement of shoulders and arms, pain) and adverse events (eg: feeling tired, peripheral nerve injury) (3) diagnosis of mental disorders (4) history of heart disease, respiratory disease (5) CNS disease, or orthopedic disease (6) history of brain or CNS radiation (7) no one to accompany when it is needed to be assited acompany

Design outcomes

Primary

Measure	Time frame
Cognitive Function: Functional Assessment of Cancer Therapy-Cognitive Function Version 3 (FACT-Cog), The Trail Making Test (TMT) Parts A and B; The time of data collection is baseline, 4 weeks and 12 weeks	—

Secondary

Measure	Time frame
Functional Assessment of Cancer Therapy-General version4 (FACT-G)	—

Countries

Japan,North America

Contacts

Public ContactMika Miyashita

Kyoto University Oncology Nursing and Palliative Care, Human Health Sciences, Graduate School of Medicine

miyashita.mika.3w@kyoto-u.ac.jp075-751-3921

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Sep 19, 2026