Kawasaki disease
Conditions
Interventions
None listed
Sponsors
Fukuoka Children's Hospital Kawasaki disease center
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Untreated Kawasaki disease patients 2. Cases with fever higher than 37.5 degrees at entry 3. Cases in which agreement before entry are obtained the parents / legal representative after explanation of the clinical trial in details
Exclusion criteria
Exclusion criteria: 1. Cases after the 9th disease day 2. Cases who is taking vitamins at the onset of Kawasaki disease 3. Cases who have coronaly artery lesion at entry 4. Recurrent or relapsed cases of Kawasaki disease 5. Cases whose cause of fever is other than Kawasaki disease 6. Cases who received immunoglobulin within 90 days before entry 7. Cases with serious underlying diseases 8. Cases taking immunosuppressive drugs such as steroids 9. Cases with other diseases that require oral administration of anticoagulants and antiplatelets 10. Cases with allergies to vitamins 11. Other cases judged by the investigator as inappropriate
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The time from the start of treatment to fever reduction | — |
Secondary
| Measure | Time frame |
|---|---|
| Hospitalization period, CRP after treatment, Ratio of refractory cases, Ratio of relapsed cases, Complication rate of coronary artery lesion(during hospitalization, 1 month after onset), change of Z-score, change of LOX-1 ligand(before treatment, after fever reduction, 1 month after onset) | — |
Countries
Japan
Contacts
Public ContactYumi Mizuno
Fukuoka Children's Hospital Kawasaki disease center
Outcome results
None listed