Multicenter clinical trial of hANP therapy on outpatient for heart failure.

Multicenter clinical trial of hANP therapy on outpatient for heart failure. - Multicenter clinical trial of hANP therapy on outpatient for heart failure.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000037125

Enrollment

100

Registered

2019-06-20

Start date

2019-04-06

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

chronic heart failure(NYHA II to III)

Interventions

hANP is administered at 0.02 to 0.1 ng/ kg /min as an outpatient for 3 to 5 hours.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Chronic heart failure (NYHA II to III) Patients from whom informed consent was obtained

Exclusion criteria

Exclusion criteria: Patients from whom informed consent was not obtained Hemodialysis Cardiogenic Shock Heart failure (NYHA IV)

Design outcomes

Primary

Measure	Time frame
Hospitalization	—

Secondary

Measure	Time frame
BNP or NT-ProBNP BUN, Cr, eGFR, AST, ALT, urinary albumin CTR on chest XP, pleural effusion Echocardiography (LVDd, LVDs, EF,% FS, E / e ', LAD)	—

Countries

Japan

Contacts

Public ContactNozomi Komoda

Nihon University Itabashi Hospital Clinical research center

komoda.nozomi@nihon-u.ac.jp03-3972-8111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026