Prospective study on evaluation of amyloid accumulation in patients suspected of both cerebral amyloid angiopathy and isolated cortical venous thrombosis using Amyloid positron emission tomography

Prospective study on evaluation of amyloid accumulation in patients suspected of both cerebral amyloid angiopathy and isolated cortical venous thrombosis using Amyloid positron emission tomography - ALPS-VACANCES

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000037101

Enrollment

Registered

2019-06-20

Start date

2019-08-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cerebral amyloid angiopathy isolated cortical venous thrombosis

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) T2* weighted image demonstrates linear low intensities along surface of the brain. 2) Neurological symptoms (including transient) correlate with the cortical linear lesions in T2* weighted image. 3) Two or more physicians diagnose that multiple cortical micro bleeds in the cerebrum or cerebellum are not conspicuous on T2* weighted image. 4) The score of Mini Mental State Examination is not matter. 5) Age and gender do not matter. 6) The written informed consent is obtained from the patient or representative.

Exclusion criteria

Exclusion criteria: 1. Highly suspected with CAA 2. Diagnosed as Alzheimer's disease 3. Contraindication for MRI (pacemaker, brain clip etc) 4. Inappropriate cases to participate in this study judged by the physicians.

Design outcomes

Primary

Measure	Time frame
Amyloid beta protein deposition with [11C] PiB PET.	—

Countries

Japan

Contacts

Public ContactYuya Kobayashi

Kohnan Hospital Department of Stroke Neurology

juri3@kohnan-sendai.or.jp0222482131

Outcome results