Pharmacokinetic of quercetin in tears following oral ingestion

Pharmacokinetic of quercetin in tears following oral ingestion - Effect of quercetin-rich onion on lacrimal gland function

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000037092

Enrollment

Registered

2019-06-18

Start date

2011-12-20

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

dry eye disease

Interventions

Onion powder (quercetin high amount) 23g/day for five days. Onion powder (quercetin low amount) 23g/day for five days.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Subjects who do not have any systemic diseases that may influence on the wound healing of eyes such as diabetes

Exclusion criteria

Exclusion criteria: Subjects who do not agree with tear collection Taking supplements Smokers

Design outcomes

Primary

Measure	Time frame
Concentration of quercetin in tear Concentration of quercetin in serum	—

Secondary

Measure	Time frame
Tear production Tear film breakup time Fuorescein corneal staining Questionnaire Concentration of oxidative stress marker in tear	—

Countries

Japan

Contacts

Public ContactTakaaki Inaba

Tokyo Dental College, Ichikawa General Hospital Ophthalmology

Prosuta@yahoo.co.jp047-322-0151

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026