Skip to content

Examination of preload reserve in patients with atrial septal defect using positive leg pressure loading method

Examination of preload reserve in patients with atrial septal defect using positive leg pressure loading method - LPP-ASD

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000037014
Enrollment
90
Registered
2019-09-01
Start date
2019-11-05
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

atrial septal defect

Interventions

We assess echocardiographic differences in stroke volume as the preload is increased in patients with atrial septal defects. Preload is to apply a pressure of 100 mmHg to both legs for 10 minutes at D

Sponsors

Kobe University Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: The control was a group having no history of heart disease and no functional or structural abnormality. The disease group includes: Those have confirmed atrial septal defect by echocardiography, cardiac CT, or imaging such as cardiac MRI, 2 Those are hemodynamically stable

Exclusion criteria

Exclusion criteria: 1.Hypertension (> 160/90 mmHg) and hypotension (<90/50 mmHg) 2.Having a history of acute other organ disease within 3 months 3.Patients with severe liver and kidney injury 4.Pregnant women 5.Patients who have or have a history of lower deep vein thrombosis 6.Patients who have injuries or skin problems at positive pressure area of lower extremity. The above was the exclusion criteria.

Design outcomes

Primary

MeasureTime frame
We compare stroke volume change by leg-positive pressure, before and after ASD occlusion and in the normal group.

Countries

Japan

Contacts

Public Contactkensuke matsumoto

Kobe University Hospital cardiovascular medicine

kenmatsu@med.kobe-u.ac.jp0783825846

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026