Investigating the tissue migration of anti-MRSA drugs in soft tissue infections

Investigating the tissue migration of anti-MRSA drugs in soft tissue infections - Investigating the tissue migration of anti-MRSA drugs in soft tissue infections

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000036933

Enrollment

Registered

2019-06-04

Start date

2019-07-31

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pressure ulcer in sacral and ischial region which have been performed flap reconstruction.

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: A total of 60 patients with bed sores who were eligible for flap formation and were infected or colonized by MRSA (patients receiving vancomycin, n = 20; those receiving daptomycin, n = 20; and those receiving linezolid, n = 20) were enrolled.

Exclusion criteria

Exclusion criteria: Patients aged under 15 years or over 100 years.

Design outcomes

Primary

Measure	Time frame
The concentration of the anti MRSA medicine in the tissue fluid, the blood plasma and tissue transitivity of the medicine, We compare the concentration using the fluid in the drainage bag and the data of blood test until 3days post operation date.	—

Countries

Japan

Contacts

Public ContactTomoya Sato

Saitama Medical University Hospital Plastic and Reconstructive surgery department

tsato11032@yahoo.co.jp0492761230

Outcome results