A Randomized Controlled Trial of The Effects of Dietary Nitrate Supplementation on Blood Pressure and Maximal Isometric Handgrip Strength in Prehypertensive Women

A Randomized Controlled Trial of The Effects of Dietary Nitrate Supplementation on Blood Pressure and Maximal Isometric Handgrip Strength in Prehypertensive Women - A Randomized Controlled Trial of The Effects of Dietary Nitrate Supplementation on Blood Pressure and Maximal Isometric Handgrip Strength in Prehypertensive Women

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000036925

Enrollment

Registered

2019-06-02

Start date

2019-06-03

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Prehypertensive

Interventions

130 mg per kg of subject body weight of beetroot extract Placebo capsule not containing beetroot extract

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: (1) persons who is generally judged as prehypertensive (two separate days systolic reading range between 120 mmHg to 139 mmHg, or the diastolic reading between 80 mmHg to 89 mmHg otherwise healthy adult

Exclusion criteria

Exclusion criteria: (1) persons who have any dietary supplements, quasi drugs or medicines which cause same or similar efficacy with the effect evaluated in this study (2) persons who have changed their habitats to take supplements within past 4 weeks. (3) Persons who work in night shift or in day and night shift (4) persons who have been treated their illness or prevention in a clinic at their informed consent (5) persons with their medical histories as follows: serious diseases of sugar metabolism, lipid metabolism, hepatic function, renal function, heart, circulatory, respiratory, endocrine system, immune system, or mental illness of the nervous system (6) persons with the medical histories of alcoholism or drug dependence (7) persons who might be developed allergic reaction to foods. (8) Persons who are pregnant, breastfeeding, or hope to be pregnant during the study period (9) persons who had always participated in or will participate in any other clinical trial (to use foods/medicine/quasi medicine/medical device) (10) persons who will not be judged suitable to the participants by the investigator.

Design outcomes

Primary

Measure	Time frame
Resting blood pressure (systolic blood pressure, diastolic blood pressure and mean arterial pressure)	—

Secondary

Measure	Time frame
Fractional exhaled nitric oxide (FeNO) Renal function (urea nitrogen, creatine, uric acid) Physical measurements (body weight, body fat percentage, waist circumference, heart beat)	—

Countries

Asia(except Japan)

Contacts

Public ContactAdam Linoby

Universiti Teknologi MARA Faculty of Sports Science and Recreation

linoby@uitm.edu.my+60133632005

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026