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Multi-component cognitive intervention with physical exercise for older adults with Alzheimer's disease: a 6-month randomized controlled trial

Multi-component cognitive intervention with physical exercise for older adults with Alzheimer's disease: a 6-month randomized controlled trial - Exercise improves cognition in Alzheimer's disease

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000036888
Enrollment
100
Registered
2019-05-30
Start date
2014-11-10
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Alzheimer&#39

Interventions

Intervention group A 6-month Multi-component cognitive program(MCP) consisting of music therapy, art therapy, horticulture therapy, handicraft, recreational therapy, gymnastics, laughing therapy, and

Sponsors

Tohoku University Graduate school, Department of Internal Medicine and Rehabilitation Science
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. A diagnosis of AD by a neurologist 2. Living in a nursing home for at least three months 3. Moderate to severe AD as determined by their baseline MMSE score of =< 20 4. Informed consent

Exclusion criteria

Exclusion criteria: 1. Not meeting inclusion criteria 2. A serious neurological diagnosis or severe cardiac, pulmonary, and musculoskeletal disorders from physician 3. Regular participation in aerobic exercise or strength training.

Design outcomes

Primary

MeasureTime frame
ADAS-cog(Alzheimer's disease assessment scale cognitive subscale)—

Secondary

MeasureTime frame
Assessment of cognitive function 1. MMSE(Mini Mental State Examination) 2. CDT(Clock Drawing Test) Assessment of physical function 1. BBS(Berg balance scale) 2. FSST(Four square step test) 3. TUG(Timed up and go test) 5. 5MWT(5-meter walk test)—

Countries

Asia(except Japan)

Contacts

Public ContactJi Kim

Tohoku University Graduate school Department of Internal Medicine and Rehabilitation Science

seraphina0414@gmail.com022-717-7353

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026