Diffusion tensor imaging study of stroke patients with upper limb paralysis. -the relationships between clinical functional changes and fractional anisotropy-

Diffusion tensor imaging study of stroke patients with upper limb paralysis. -the relationships between clinical functional changes and fractional anisotropy- - Diffusion tensor imaging study of stroke patients with upper limb paralysis. -the relationships between clinical functional changes and fractional anisotropy-

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000036811

Enrollment

Registered

2019-05-21

Start date

2019-05-17

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

stroke healthy control

Interventions

Subjects undergo a medical examination by a neurologist and DTI. Subjects undergo a standard rehabilitation (physical therapy, occupational therapy, speech therapy) for six weeks. Subjects undergo DTI

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: <Patients> 1.Clinically incipient supratentorial stroke patients with upper-limb hemiplegia 2.Patients who experienced a stroke within 6 months 3.Mini Mental State Examination>=24 4.ADL before onset was independent 5.Dextrality 6.No contraindication to magnetic resonance imaging <Normal Controls> 1.Dextrality 2.Mini Mental State Examination>=24, result of Trail Making Test-Japan is no abnormality 3.Living everyday life without any problems, even if there is a risk factor for cerebrovascular disease (e.g.hypertension and diabetes mellitus) 4.No contraindication to magnetic resonance imaging 5.No history of cerebrovascular disease, traumatic brain injury and dementia 6.No neurological symptoms (no paretic symptoms and no hyperactive deep tendon reflex)

Exclusion criteria

Exclusion criteria: <Patients> 1.Severe aphasia 2.Cause other neuromuscular complications 3.Undergo surgical treatments 4.Consciousness disorders, psychiatric disorders 5.Having obvious neurological symptoms

Design outcomes

Primary

Measure	Time frame
Fractional anisotropy value of Healthy control (after informed consent) and patients (at admission and 6 weeks later)	—

Secondary

Measure	Time frame
Listed assessments of patients at admission and 6 weeks later. <Impairment assessment of U/E> 1.Fugl-Meyer Assessment(FMA) : U/E 2.Brunnstrom Stage (BS) : U/E, finger 3.STEF : All item <Functional assessment of U/E> 4.Functional Independence Measure (FIM) : all 18 items 5.Motor Activity Log (MAL) : 14 items	—

Countries

Japan

Contacts

Public ContactNaoya Anmoto

Nagoya City Rehabilitation Agency Division of Occupational Therapy

ot-dep@nagoya-rehab.or.jp052-835-3811

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026