Effect of periodontitis on gut microbiome.

Verification of the effect of oral dysbiosis on gut dysbiosis. - Verification of the effect of oral dysbiosis on gut dysbiosis.

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000036801

Enrollment

Registered

2019-05-24

Start date

2019-03-05

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Periodontitis

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Diagnosed as chronic or aggressive periodontitis Good general health without any remarkable past history except well controlled hypertension and dyslipidemia Presence of at least 15 remaining teeth; presence of at least 2 teeth with probing pocket depth. > 5 mm with concomitant bleeding on probing.

Exclusion criteria

Exclusion criteria: Use of systemic antimicrobials in the past 3 months. Being pregnant or suspected pregnancy. Having uncontrolled diabetes, severe heart disease, kidney dysfunction, or other diseases not suitable for this investigation.

Design outcomes

Primary

Measure	Time frame
Gut microbiome	—

Secondary

Measure	Time frame
Saliva microbiome	—

Countries

Japan

Contacts

Public ContactKeisuke Sato

Niigata University Graduate School of Medical and Dental Sciences Division of Peridontology

keisuke@dent.niigata-u.ac.jp81252272872

Outcome results