Study for influence of long-term intake of pineapple on improvement in intestinal environment and skin condition

Study for influence of long-term intake of pineapple on improvement in intestinal environment and skin condition - Study for influence of long-term intake of pineapple on improvement in intestinal environment and skin condition

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000036740

Enrollment

Registered

2019-05-14

Start date

2019-06-22

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy Adults

Interventions

Intake 100g of pineapple per day. none

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1.Those who received a sufficient explanation of the purpose and contents of the exam, have the capacity to consent, applied with free will with sufficient understanding, and agreed to participate with a written document 2.Healthy Japanese those who are over 20 years old and under 60 at the time of consent acquisition 3.Those who defecate 2 to 4 times a week 4.Those who are concerned about rough skin, skin dullness, skin dryness, skin sagging, skin stains, etc.

Exclusion criteria

Exclusion criteria: 1.Those who have a chronic disease and are undergoing medication, those with a serious disease history 2.Those who have skin lesions such as atopic dermatitis, urticaria, eczema and dermatitis 3.Those who are allergic to the test food 4.Those who have participated in other tests within the first month before the start of the exam, or who are planning to participate in other exams after this exam consent 5.Those who are judged ineligible at the discretion of the examining supervisor and research leader 6.Those who are breast-feeding, pregnant, and are planning or hoping pregnancy during the exam

Design outcomes

Primary

Measure	Time frame
Intestinal bacterial flora before and after intake of 8 weeks	—

Secondary

Measure	Time frame
Face skin image (stain, wrinkle, pores, skin color uniformity, porphyrin) Transepidermal water loss (cheeks, arms) Skin water content (cheeks, arms) Amount of skin melanin and erythema (cheeks, arms) Skin color difference (cheeks, arms) Physical examination (body height, weight, BMI) Questionnaire on defecation Awareness questionnaire about skin (VAS) Urine test (Indoxyl sulfate) before and after intake of 8 weeks	—

Measure

Time frame

Face skin image (stain, wrinkle, pores, skin color uniformity, porphyrin) Transepidermal water loss (cheeks, arms) Skin water content (cheeks, arms) Amount of skin melanin and erythema (cheeks, arms) Skin color difference (cheeks, arms) Physical examination (body height, weight, BMI) Questionnaire on defecation Awareness questionnaire about skin (VAS) Urine test (Indoxyl sulfate) before and after intake of 8 weeks

—

Countries

Japan

Contacts

Public ContactTakamasa Masuda

Healthcare Systems Co., Ltd. Research and Development Department

masudat@hc-sys.jp03-6809-2722

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026