Association between carperitide infusion and shedding of the endothelial glycocalyx in cardiac surgical patients

Association between carperitide infusion and shedding of the endothelial glycocalyx in cardiac surgical patients - Carperitide infusion and shedding of the endothelial glycocalyx in cardiac surgical patients

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000036677

Enrollment

Registered

2019-05-08

Start date

2020-10-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative cardiac surgery patients recieving carperitide infusion therapy

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Postcardiac surgery patients who scheduled to start carperitide infusion therapy in the intensive care unit.

Exclusion criteria

Exclusion criteria: 1.A patient who have had recieved carperitide infusion within 12h 2.A patient with wobbly tooth 3.A patient who have surgical history of tongue 4.A patient without any indwelling arterial line 5.A patient determined to be inappropriate as a research subject by the principal investigator

Design outcomes

Primary

Measure	Time frame
Change in Perfused Boundary Region (PBR) [Time frame: just before the start of carperitide infusion, 1h, 2h, 6h after the start of infusion]	—

Secondary

Measure	Time frame
Change in plasma syndecan-1 concentration, RBC column width, RBC filling [Time frame: just before the start of carperitide infusion, 1h, 2h, 6h after the start of infusion]	—

Countries

Japan

Contacts

Public ContactKazuyuki Mizunoya

Hokkaido University Hospital Anesthesiology

kazuyuki_mizunoya@hotmail.com011-716-1161

Outcome results