Single-arm feasibility study of laparoscopic gastrectomy for upper-third gastric cancer and esophago-gastric junction cancer

Single-arm feasibility study of laparoscopic gastrectomy for upper-third gastric cancer and esophago-gastric junction cancer - Single-arm feasibility study of laparoscopic gastrectomy for upper-third gastric cancer and esophago-gastric junction cancer

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000036621

Enrollment

200

Registered

2019-10-01

Start date

2019-10-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Upper-third gastric cancer and esophago-gastric junction cancer

Interventions

Laparoscopic proximal gastrectomy or laparoscopic total gastrectomy

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) Pathologically diagnosed as gastric or esophago-gastric adenocarcinoma. 2) Curatively resectable cT1N2-3M0, cT2N0-3M0, cT3N0M0 and cT4N0M0 (excluding bulky N2) cancer by proximal or total gastrectomy without splenectomy. 3) Older than 20 y.o. 4) PS 0~2 5) No previous treatment for gastric cancer. 6) BMI<35 7) Consented to be enrolled to the trial from participant him/herself.

Exclusion criteria

Exclusion criteria: 1) Double cancer 2) cT4b 3) P1, Cy1 or cM1 4) Cases of received neoadjuvant treatment. 5) Pregnant or breast feeding. 6) Mental disorder 7) Continuous systemic administration of steroid. 8) Infectious disease with systemic treatment. 9) Uncontrollable diabetes mellitus. 10) Unstable coronary angina or history of MI within 6 months. 11) Respiratory disease with continuous administration of oxygen.

Design outcomes

Primary

Measure	Time frame
Incidence of anastomotic leakage	—

Countries

Japan

Contacts

Public ContactEn Amada

Cancer Institute Hospital of JFCR Gastroenterology Center

en.amada@jfcr.or.jp+81-3-3520-0111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026