Temporal Lobe Epilepsy
Conditions
Interventions
Facial emotion recognition task Magnetoencephalography (MEG) Brain MRI
Sponsors
Department of Neurology, Neurological Institute, Graduate School of Medicine, Kyushu University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Patients with clinically diagnosed or highly suspected temporal lobe epilepsy 2. Patients are evaluated by board certified epileptologists. Focal epilepsy is defined as follows; (A) at least two unprovoked seizures occurring greater than 24 hours apart (B) localization is evidenced by at least one of the following examinations; EEG recording, MRI, FDG-PET, SPECT or MEG (C) ictal semiology is compatible to the lesions detected by examinations 3. No visual disability 4. Right handed 5. Fluent in written and spoken Japanese
Exclusion criteria
Exclusion criteria: 1. History of epilepsy surgery 2. Neurological and psychiatric comorbidities 3. Any contraindications to MRI or MEG
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The amplitude and latency differences of emotional face evoked M170 between healthy control and temporal lobe epilepsy | — |
Secondary
| Measure | Time frame |
|---|---|
| The relationship between performance of facial emotion recognition and volume changes in amygdala, hippocampus and cerebral cortices The relationship between the amplitude and latency of emotional face evoked M170 and volume changes in amygdala, hippocampus and cerebral cortices | — |
Countries
Japan
Contacts
Public ContactTaira Uehara
Graduate School of Medicine, Kyushu University Department of Clinical Neurophysiology, Neurological Institute
Outcome results
None listed